Electrothermal Supercharging in Mass Spectrometry and Tandem Mass Spectrometry of Native Proteins
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چکیده
منابع مشابه
Desalting protein ions in native mass spectrometry using supercharging reagents.
Effects of the supercharging reagents m-NBA and sulfolane on sodium ion adduction to protein ions formed using native mass spectrometry were investigated. There is extensive sodium adduction on protein ions formed by electrospray ionization from aqueous solutions containing millimolar concentrations of NaCl, which can lower sensitivity by distributing the signal of a given charge state over mul...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2012
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac302256d